Genética de grupos sangüíneos ABH e LEWIS: revisão da literatura
DOI:
https://doi.org/10.46311/2318-0579.9.eUJ490Resumen
Os antígenos ABH e Lewis são oligossacarídeos, e estão relacionados
bioquimicamente, pois são produzidos a partir das mesmas substâncias
precursoras. A biossíntese de cadeias oligossacarídicas implica a
participação de várias glicosiltransferases, produtos dos genes do sistema
ABO, Hh, Sese e Lele. Estes antígenos são expressos nos eritrócitos,
tecidos e fluidos corporais. A via biosintética ocorre de maneira
diferenciada nas hemácias e em células de outros tecidos. Muito tem se
questionado a respeito da relação entre os antígenos de grupos sangüíneos
ABH e Lewis e as doenças. Esses antígenos são receptores de inúmeros
microorganismos.
Descargas
Descargas
Publicado
Cómo citar
Número
Sección
Licencia
I declare/we declare that the text submitted here is original, of my own authorship and does not infringe any type of third party rights. The content is my/our sole responsibility. Possible research involving animals and/or human beings is in accordance with Resolution 196/96 of the National Health Council and its complements. I declare that I am/we are in possession of the written consent of patients and that the research and its procedures were timely and adequately approved by the Ethics Committee of the institution of origin. We further declare that all institutional affiliations and all sources of financial support for the work are duly informed. I certify that there is no commercial or associative interest that represents a conflict of interest related to the submitted work. If there is commercial interest, in addition to the technical and academic ones, in the publication of the article, the information will be reported during the text.
