Desenvolvimento e validação de metodologia para a certificação da pureza enantiomérica do Efavirenz
DOI:
https://doi.org/10.46311/2318-0579.2.eUJ360Abstract
Uma metodologia simples, por CLAE (Cromatografia Líquida de Alta Eficiência)
quiral, foi desenvolvida e validada para a determinação da pureza enantiomérica do
efavirenz. A metodologia foi desenvolvida utilizando-se uma coluna quiral com fase
tris[(S)-1-feniletilcarbamato] de amilose, no modo reverso de eluição utilizando
ACN/H2O (53:47 v/v) como fase móvel. A metodologia desenvolvida pode ser utilizada
na indústria farmacêutica para análises de rotina e certificação de matéria-prima e
produto acabado.
Downloads
Downloads
Published
How to Cite
Issue
Section
License
I declare/we declare that the text submitted here is original, of my own authorship and does not infringe any type of third party rights. The content is my/our sole responsibility. Possible research involving animals and/or human beings is in accordance with Resolution 196/96 of the National Health Council and its complements. I declare that I am/we are in possession of the written consent of patients and that the research and its procedures were timely and adequately approved by the Ethics Committee of the institution of origin. We further declare that all institutional affiliations and all sources of financial support for the work are duly informed. I certify that there is no commercial or associative interest that represents a conflict of interest related to the submitted work. If there is commercial interest, in addition to the technical and academic ones, in the publication of the article, the information will be reported during the text.
.png)
